Most runs in a Major League career
- WHO
- Rickey Henley Henderson
- WHERE
- United States
- WHEN
- 2003
The most runs scored in a Major League Baseball (MLB) career is 2,295 by Rickey Henderson (USA) while playing for the Oakland Athletics, New York Yankees (both USA), Toronto Blue Jays (Canada), San Diego Padres, Anaheim Angels, New York Mets, Seattle Mariners, Boston Red Sox and Los Angeles Dodgers (all USA) from 1979 to 2003.